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Simvastatin vs Atorvastatin

When is the best time to take medication?

 

Choosing between atorvastatin and simvastatin involves considering their distinct characteristics.

 

✅ Atorvastatin, recommended for morning intake, boasts potency and a prolonged half-life (14 hours), ensuring a consistent reduction in cholesterol throughout the day.

 

Eg : T. Atorvastatin 40mg OD/ON

 

✅ Simvastatin, on the other hand, is shorter half life (<5 hours) hence suggested for nighttime consumption to align with the body's peak cholesterol synthesis during those hours. This strategic timing optimizes simvastatin's effectiveness in targeting nighttime cholesterol production   Eg : T. Simvastatin 40mg ON   Papisma Kedah

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